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[[Image:2g3h.png|left|200px]]


{{STRUCTURE_2g3h|  PDB=2g3h  |  SCENE=  }}
==Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin==
 
<StructureSection load='2g3h' size='340' side='right'caption='[[2g3h]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
===Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2g3h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3H FirstGlance]. <br>
{{ABSTRACT_PUBMED_16906763}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3h OCA], [https://pdbe.org/2g3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3h RCSB], [https://www.ebi.ac.uk/pdbsum/2g3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3h ProSAT]</span></td></tr>
[[2g3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3H OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9VF15_DROME Q9VF15_DROME]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3h ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Hemoglobin|Hemoglobin]]
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016906763</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Ascenzi, P.]]
[[Category: Large Structures]]
[[Category: Bocedi, A.]]
[[Category: Ascenzi P]]
[[Category: Bolognesi, M.]]
[[Category: Bocedi A]]
[[Category: Burmester, T.]]
[[Category: Bolognesi M]]
[[Category: Dewilde, S.]]
[[Category: Burmester T]]
[[Category: Hankeln, T.]]
[[Category: Dewilde S]]
[[Category: Moens, L.]]
[[Category: Hankeln T]]
[[Category: Sanctis, D de.]]
[[Category: Moens L]]
[[Category: Cyanide binding to hemoglobin]]
[[Category: De Sanctis D]]
[[Category: Drosophila melanogaster hemoglobin structure]]
[[Category: Fruit fly hemoglobin]]
[[Category: Heme distal site structure]]
[[Category: Hexa-coordinate hemoglobin]]
[[Category: Transport protein]]

Latest revision as of 12:26, 14 February 2024

Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate HemoglobinCyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin

Structural highlights

2g3h is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.4Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9VF15_DROME

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2g3h, resolution 1.40Å

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OCA