1x8x: Difference between revisions

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-[[Image:1x8x.png|left|200px]]
-{{STRUCTURE_1x8x|  PDB=1x8x  |  SCENE=  }}
+==Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine==
+<StructureSection load='1x8x' size='340' side='right'caption='[[1x8x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1x8x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X8X FirstGlance]. <br>
-{{ABSTRACT_PUBMED_15663931}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x8x OCA], [https://pdbe.org/1x8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x8x RCSB], [https://www.ebi.ac.uk/pdbsum/1x8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x8x ProSAT], [https://www.topsan.org/Proteins/RSGI/1x8x TOPSAN]</span></td></tr>
-[[1x8x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X8X OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SYY_ECOLI SYY_ECOLI] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02006]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x8x_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x8x ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:015663931</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Tyrosine--tRNA ligase]]
+[[Category: Large Structures]]
-[[Category: Kamata, K.]]
+[[Category: Kamata K]]
-[[Category: Kelly, V P.]]
+[[Category: Kelly VP]]
-[[Category: Kobayashi, T.]]
+[[Category: Kobayashi T]]
-[[Category: Nishimura, S.]]
+[[Category: Nishimura S]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Sakamoto K]]
-[[Category: Sakamoto, K.]]
+[[Category: Sekine R]]
-[[Category: Sekine, R.]]
+[[Category: Takimura T]]
-[[Category: Takimura, T.]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S.]]
-[[Category: Ligase]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]