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[[Image:1fwt.png|left|200px]]


{{STRUCTURE_1fwt|  PDB=1fwt  |  SCENE=  }}
==AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, E4P AND CADMIUM==
 
<StructureSection load='1fwt' size='340' side='right'caption='[[1fwt]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, E4P AND CADMIUM===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1fwt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FWT FirstGlance]. <br>
{{ABSTRACT_PUBMED_11115499}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=E4P:ERYTHOSE-4-PHOSPHATE'>E4P</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fwt OCA], [https://pdbe.org/1fwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fwt RCSB], [https://www.ebi.ac.uk/pdbsum/1fwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fwt ProSAT]</span></td></tr>
[[1fwt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FWT OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/KDSA_AQUAE KDSA_AQUAE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/1fwt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fwt ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldolase|Aldolase]]
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:011115499</ref><references group="xtra"/>
[[Category: 3-deoxy-8-phosphooctulonate synthase]]
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Duewel, H S.]]
[[Category: Large Structures]]
[[Category: Gatti, D L.]]
[[Category: Duewel HS]]
[[Category: Radaev, S.]]
[[Category: Gatti DL]]
[[Category: Wang, J.]]
[[Category: Radaev S]]
[[Category: Woodard, R W.]]
[[Category: Wang J]]
[[Category: A5p]]
[[Category: Woodard RW]]
[[Category: Beta/alpha barrel]]
[[Category: Kdo]]
[[Category: Kdo8p]]
[[Category: Kdo8p]]
[[Category: Lyase]]
[[Category: Pep]]

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