4al4: Difference between revisions

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[[Image:4al4.png|left|200px]]


{{STRUCTURE_4al4|  PDB=4al4  |  SCENE=  }}
==rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy)phenyl)methylpropanedioic acid==
 
<StructureSection load='4al4' size='340' side='right'caption='[[4al4]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
===rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy)phenyl)methylpropanedioic acid===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4al4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AL4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22417091}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=W7E:2-[[4-[2-[[3-[(2-METHYL-1,3-BENZOTHIAZOL-6-YL)AMINO]-3-OXIDANYLIDENE-PROPYL]CARBAMOYLAMINO]ETHOXY]PHENYL]METHYL]PROPANEDIOIC+ACID'>W7E</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4al4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4al4 OCA], [https://pdbe.org/4al4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4al4 RCSB], [https://www.ebi.ac.uk/pdbsum/4al4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4al4 ProSAT]</span></td></tr>
[[4al4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AL4 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHA_RAT LDHA_RAT]


==See Also==
==See Also==
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022417091</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: L-lactate dehydrogenase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Brassington, C.]]
[[Category: Brassington C]]
[[Category: Davies, G.]]
[[Category: Davies G]]
[[Category: Hassall, G.]]
[[Category: Hassall G]]
[[Category: Hohson, M.]]
[[Category: Hohson M]]
[[Category: Pearson, S.]]
[[Category: Pearson S]]
[[Category: Tart, J.]]
[[Category: Tart J]]
[[Category: Tucker, J A.]]
[[Category: Tucker JA]]
[[Category: Ward, R.]]
[[Category: Ward R]]
[[Category: Fragment based lead generated inhibitor]]
[[Category: Oxidoreductase-inhibitor complex]]

Latest revision as of 10:15, 1 May 2024

rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy)phenyl)methylpropanedioic acidrat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy)phenyl)methylpropanedioic acid

Structural highlights

4al4 is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.78Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LDHA_RAT

See Also

4al4, resolution 1.78Å

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