1np8: Difference between revisions

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-[[Image:1np8.png|left|200px]]
-{{STRUCTURE_1np8|  PDB=1np8  |  SCENE=  }}
+==18-k C-terminally trunucated small subunit of calpain==
+<StructureSection load='1np8' size='340' side='right'caption='[[1np8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===18-k C-terminally trunucated small subunit of calpain===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1np8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NP8 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_14579356}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1np8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1np8 OCA], [https://pdbe.org/1np8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1np8 RCSB], [https://www.ebi.ac.uk/pdbsum/1np8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1np8 ProSAT]</span></td></tr>
-[[1np8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NP8 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CPNS1_RAT CPNS1_RAT] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/1np8_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1np8 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Calpain|Calpain]]
+*[[Calpain 3D structures|Calpain 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:014579356</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Arthur, J S.]]
+[[Category: Arthur JS]]
-[[Category: Davies, P L.]]
+[[Category: Davies PL]]
-[[Category: Elce, J S.]]
+[[Category: Elce JS]]
-[[Category: Grochulski, P.]]
+[[Category: Grochulski P]]
-[[Category: Jia, Z.]]
+[[Category: Jia Z]]
-[[Category: Leinala, E K.]]
+[[Category: Leinala EK]]
-[[Category: Dimer in solution]]
-[[Category: Hydrolase]]
-[[Category: Oligomer in crystal]]