3beh: Difference between revisions

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[[Image:3beh.png|left|200px]]


{{STRUCTURE_3beh|  PDB=3beh  |  SCENE=  }}
==Structure of a Bacterial Cyclic Nucleotide Regulated Ion Channel==
 
<StructureSection load='3beh' size='340' side='right'caption='[[3beh]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
===Structure of a Bacterial Cyclic Nucleotide Regulated Ion Channel===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3beh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BEH FirstGlance]. <br>
{{ABSTRACT_PUBMED_18216238}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3beh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3beh OCA], [https://pdbe.org/3beh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3beh RCSB], [https://www.ebi.ac.uk/pdbsum/3beh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3beh ProSAT]</span></td></tr>
[[3beh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEH OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNGK1_RHILO CNGK1_RHILO] Cyclic nucleotide-regulated potassium channel activated by cAMP.<ref>PMID:15550244</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/be/3beh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3beh ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Ion channels|Ion channels]]
*[[Ion channels 3D structures|Ion channels 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:018216238</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mesorhizobium loti]]
[[Category: Mesorhizobium loti]]
[[Category: Clayton, G M.]]
[[Category: Clayton GM]]
[[Category: Morais-Cabral, J H.]]
[[Category: Morais-Cabral JH]]
[[Category: Membrane protein]]
[[Category: Transmembrane protein]]

Latest revision as of 12:28, 21 February 2024

Structure of a Bacterial Cyclic Nucleotide Regulated Ion ChannelStructure of a Bacterial Cyclic Nucleotide Regulated Ion Channel

Structural highlights

3beh is a 4 chain structure with sequence from Mesorhizobium loti. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CNGK1_RHILO Cyclic nucleotide-regulated potassium channel activated by cAMP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Clayton GM, Silverman WR, Heginbotham L, Morais-Cabral JH. Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell. 2004 Nov 24;119(5):615-27. PMID:15550244 doi:10.1016/j.cell.2004.10.030

3beh, resolution 3.10Å

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