3ld5: Difference between revisions

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-[[Image:3ld5.png|left|200px]]
-{{STRUCTURE_3ld5|  PDB=3ld5  |  SCENE=  }}
+==Human aldose reductase mutant T113S complexed with IDD594==
+<StructureSection load='3ld5' size='340' side='right'caption='[[3ld5]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
-===Human aldose reductase mutant T113S complexed with IDD594===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3ld5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LD5 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_21185307}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.27&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ld5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ld5 OCA], [https://pdbe.org/3ld5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ld5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ld5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ld5 ProSAT]</span></td></tr>
-[[3ld5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD5 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
 ==See Also==
-*[[Aldose Reductase|Aldose Reductase]]
+*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:021185307</ref><references group="xtra"/>
-[[Category: Aldehyde reductase]]
 [[Category: Homo sapiens]]
-[[Category: Heine, A.]]
+[[Category: Large Structures]]
-[[Category: Klebe, G.]]
+[[Category: Heine A]]
-[[Category: Koch, C.]]
+[[Category: Klebe G]]
-[[Category: Nadp]]
+[[Category: Koch C]]
-[[Category: Oxidoreductase]]
-[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
-[[Category: Phosphoprotein]]
-[[Category: T113s mutant]]
-[[Category: Tim barrel]]