1ryq: Difference between revisions

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[[Image:1ryq.png|left|200px]]


{{STRUCTURE_1ryq|  PDB=1ryq  |  SCENE=  }}
==Putative DNA-directed RNA polymerase, subunit e'' from Pyrococcus Furiosus Pfu-263306-001==
 
<StructureSection load='1ryq' size='340' side='right'caption='[[1ryq]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
===Putative DNA-directed RNA polymerase, subunit e'' from Pyrococcus Furiosus Pfu-263306-001===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1ryq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RYQ FirstGlance]. <br>
{{ABSTRACT_PUBMED_15858261}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ryq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ryq OCA], [https://pdbe.org/1ryq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ryq RCSB], [https://www.ebi.ac.uk/pdbsum/1ryq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ryq ProSAT], [https://www.topsan.org/Proteins/SECSG/1ryq TOPSAN]</span></td></tr>
[[1ryq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYQ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPT4_PYRFU SPT4_PYRFU] Stimulates transcription elongation.<ref>PMID:21386817</ref> <ref>PMID:21187417</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ry/1ryq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ryq ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:015858261</ref><ref group="xtra">PMID:015930619</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Adams, M W.W.]]
[[Category: Adams MWW]]
[[Category: Brereton, P S.]]
[[Category: Arendall III WB]]
[[Category: Chen, L.]]
[[Category: Brereton PS]]
[[Category: II, F L.Poole.]]
[[Category: Chen L]]
[[Category: III, W B.Arendall.]]
[[Category: Izumi M]]
[[Category: Izumi, M.]]
[[Category: Jenney Jr FE]]
[[Category: Jenney, F E.]]
[[Category: Lee HS]]
[[Category: Lee, H S.]]
[[Category: Liu Z-J]]
[[Category: Liu, Z J.]]
[[Category: Poole II FL]]
[[Category: Richardson, D C.]]
[[Category: Richardson DC]]
[[Category: Richardson, J S.]]
[[Category: Richardson JS]]
[[Category: Rose, J P.]]
[[Category: Rose JP]]
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
[[Category: Shah A]]
[[Category: Shah, A.]]
[[Category: Shah C]]
[[Category: Shah, C.]]
[[Category: Sugar FJ]]
[[Category: Sugar, F J.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Wang B-C]]
[[Category: Wang, B C.]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Rna polymerase]]
[[Category: Secsg]]
[[Category: Southeast collaboratory for structural genomic]]
[[Category: Structural genomic]]
[[Category: Transferase]]

Latest revision as of 11:26, 14 February 2024

Putative DNA-directed RNA polymerase, subunit e from Pyrococcus Furiosus Pfu-263306-001Putative DNA-directed RNA polymerase, subunit e from Pyrococcus Furiosus Pfu-263306-001

Structural highlights

1ryq is a 1 chain structure with sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.38Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

SPT4_PYRFU Stimulates transcription elongation.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Martinez-Rucobo FW, Sainsbury S, Cheung AC, Cramer P. Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. EMBO J. 2011 Mar 8. PMID:21386817 doi:10.1038/emboj.2011.64
  2. ↑ Klein BJ, Bose D, Baker KJ, Yusoff ZM, Zhang X, Murakami KS. RNA polymerase and transcription elongation factor Spt4/5 complex structure. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):546-50. Epub 2010 Dec 27. PMID:21187417 doi:10.1073/pnas.1013828108

1ryq, resolution 1.38Å

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