3cjb: Difference between revisions

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[[Image:3cjb.png|left|200px]]


{{STRUCTURE_3cjb|  PDB=3cjb  |  SCENE=  }}
==Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1==
 
<StructureSection load='3cjb' size='340' side='right'caption='[[3cjb]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
===Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3cjb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CJB FirstGlance]. <br>
{{ABSTRACT_PUBMED_19015515}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cjb OCA], [https://pdbe.org/3cjb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cjb RCSB], [https://www.ebi.ac.uk/pdbsum/3cjb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cjb ProSAT]</span></td></tr>
[[3cjb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJB OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cjb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cjb ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Actin|Actin]]
*[[Actin 3D structures|Actin 3D structures]]
*[[Gelsolin|Gelsolin]]
*[[Gelsolin 3D structures|Gelsolin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:019015515</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Kudryashov, D S.]]
[[Category: Kudryashov DS]]
[[Category: Pashkov, I.]]
[[Category: Pashkov I]]
[[Category: Reisler, E.]]
[[Category: Reisler E]]
[[Category: Sawaya, M R.]]
[[Category: Sawaya MR]]
[[Category: Yeates, T O.]]
[[Category: Yeates TO]]
[[Category: Actin capping]]
[[Category: Actin-binding]]
[[Category: Alternative initiation]]
[[Category: Amyloid]]
[[Category: Atp-binding]]
[[Category: Cross-linked dimer]]
[[Category: Cytoskeleton]]
[[Category: Disease mutation]]
[[Category: Methylation]]
[[Category: Muscle protein]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Secreted]]
[[Category: Structural protein]]

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