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==Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant== | |||
<StructureSection load='2lc9' size='340' side='right'caption='[[2lc9]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2lc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LC9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lc9 OCA], [https://pdbe.org/2lc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lc9 RCSB], [https://www.ebi.ac.uk/pdbsum/2lc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lc9 ProSAT]</span></td></tr> | |||
== | </table> | ||
[[2lc9]] is a 1 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> | |||
==See Also== | ==See Also== | ||
*[[ | *[[Lysozyme 3D structures|Lysozyme 3D structures]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Escherichia virus T4]] | ||
[[Category: Bah | [[Category: Large Structures]] | ||
[[Category: Baker | [[Category: Bah A]] | ||
[[Category: Bouvignies | [[Category: Baker D]] | ||
[[Category: Correia | [[Category: Bouvignies G]] | ||
[[Category: Dahlquist | [[Category: Correia B]] | ||
[[Category: Hansen | [[Category: Dahlquist FW]] | ||
[[Category: Kay | [[Category: Hansen D]] | ||
[[Category: Lange | [[Category: Kay LE]] | ||
[[Category: Vallurupalli | [[Category: Lange O]] | ||
[[Category: Vernon | [[Category: Vallurupalli P]] | ||
[[Category: Vernon RM]] | |||
Latest revision as of 09:55, 1 May 2024
Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme MutantSolution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant
Structural highlights
FunctionENLYS_BPT4 Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.[1] See AlsoReferences
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