1cxv: Difference between revisions

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[[Image:1cxv.png|left|200px]]


{{STRUCTURE_1cxv|  PDB=1cxv  |  SCENE=  }}
==STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)==
 
<StructureSection load='1cxv' size='340' side='right'caption='[[1cxv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1cxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CXV FirstGlance]. <br>
{{ABSTRACT_PUBMED_10525409}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CBP:2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE'>CBP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cxv OCA], [https://pdbe.org/1cxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cxv RCSB], [https://www.ebi.ac.uk/pdbsum/1cxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cxv ProSAT]</span></td></tr>
[[1cxv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXV OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/MMP13_MOUSE MMP13_MOUSE] Degrades collagen type I.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/1cxv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cxv ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Matrix metalloproteinase|Matrix metalloproteinase]]
*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010525409</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Botos, I.]]
[[Category: Botos I]]
[[Category: Eeckhout, Y.]]
[[Category: Eeckhout Y]]
[[Category: Lemaitre, V.]]
[[Category: Lemaitre V]]
[[Category: Meyer, E.]]
[[Category: Meyer E]]
[[Category: Meyer, E F.]]
[[Category: Meyer EF]]
[[Category: Swanson, S M.]]
[[Category: Swanson SM]]
[[Category: Collagen degradation]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Metalloprotease]]

Latest revision as of 09:46, 7 February 2024

STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)

Structural highlights

1cxv is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MMP13_MOUSE Degrades collagen type I.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1cxv, resolution 2.00Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA