1k25: Difference between revisions

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-[[Image:1k25.png|left|200px]]
-{{STRUCTURE_1k25|  PDB=1k25  |  SCENE=  }}
+==PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate==
+<StructureSection load='1k25' size='340' side='right'caption='[[1k25]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-===PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1k25]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K25 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_11553637}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k25 OCA], [https://pdbe.org/1k25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k25 RCSB], [https://www.ebi.ac.uk/pdbsum/1k25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k25 ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1k25]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K25 OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/O34006_STREE O34006_STREE]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/1k25_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k25 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Penicillin-binding protein|Penicillin-binding protein]]
+*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:011553637</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Streptococcus pneumoniae]]
-[[Category: Dessen, A.]]
+[[Category: Dessen A]]
-[[Category: Dideberg, O.]]
+[[Category: Dideberg O]]
-[[Category: Hopkins, J.]]
+[[Category: Hopkins J]]
-[[Category: Mouz, N.]]
+[[Category: Mouz N]]
-[[Category: Antibiotic resistance]]
-[[Category: Clinical mutant]]
-[[Category: Low-affinity penicillin-binding]]
-[[Category: Membrane protein]]