3raf: Difference between revisions

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-[[Image:3raf.png|left|200px]]
-{{STRUCTURE_3raf|  PDB=3raf  |  SCENE=  }}
+==Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae==
+<StructureSection load='3raf' size='340' side='right'caption='[[3raf]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
-===Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3raf]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RAF FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PDQ:3-AMINO-7-{(3R)-3-[(1S)-1-AMINOETHYL]PYRROLIDIN-1-YL}-1-CYCLOPROPYL-6-FLUORO-8-METHYLQUINAZOLINE-2,4(1H,3H)-DIONE'>PDQ</scene></td></tr>
-[[3raf]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAF OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3raf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3raf OCA], [https://pdbe.org/3raf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3raf RCSB], [https://www.ebi.ac.uk/pdbsum/3raf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3raf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
 ==See Also==
-*[[Topoisomerase|Topoisomerase]]
+*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Streptococcus pneumoniae]]
-[[Category: Fisher, L M.]]
+[[Category: Fisher LM]]
-[[Category: Laponogov, I.]]
+[[Category: Laponogov I]]
-[[Category: McAuley, K E.]]
+[[Category: McAuley KE]]
-[[Category: Pan, X S.]]
+[[Category: Pan X-S]]
-[[Category: Sanderson, M R.]]
+[[Category: Sanderson MR]]
-[[Category: Veselkov, D A.]]
+[[Category: Veselkov DA]]
-[[Category: Isomerase-dna-antibiotic complex]]
-[[Category: Protein-dna cleavage complex]]
-[[Category: Quinazolinedione pd 0305970]]
-[[Category: Topoisomerase iia]]