1f4l: Difference between revisions

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-[[Image:1f4l.png|left|200px]]
-{{STRUCTURE_1f4l|  PDB=1f4l  |  SCENE=  }}
+==CRYSTAL STRUCTURE OF THE E.COLI METHIONYL-TRNA SYNTHETASE COMPLEXED WITH METHIONINE==
+<StructureSection load='1f4l' size='340' side='right'caption='[[1f4l]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-===CRYSTAL STRUCTURE OF THE E.COLI METHIONYL-TRNA SYNTHETASE COMPLEXED WITH METHIONINE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1f4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F4L FirstGlance]. <br>
-{{ABSTRACT_PUBMED_11243794}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f4l OCA], [https://pdbe.org/1f4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f4l RCSB], [https://www.ebi.ac.uk/pdbsum/1f4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f4l ProSAT]</span></td></tr>
-[[1f4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F4L OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SYM_ECOLI SYM_ECOLI] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.[HAMAP-Rule:MF_00098]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f4/1f4l_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f4l ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:011243794</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Methionine--tRNA ligase]]
+[[Category: Large Structures]]
-[[Category: Chonowski, T.]]
+[[Category: Chonowski T]]
-[[Category: Hervouet, N.]]
+[[Category: Hervouet N]]
-[[Category: Serre, L.]]
+[[Category: Serre L]]
-[[Category: Verdon, G.]]
+[[Category: Verdon G]]
-[[Category: Zelwer, C.]]
+[[Category: Zelwer C]]
-[[Category: Amino acid]]
-[[Category: Hydrolase]]
-[[Category: Rossmann fold]]
-[[Category: Trna]]
-[[Category: Zinc domain]]