2ouc: Difference between revisions

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-[[Image:2ouc.png|left|200px]]
-{{STRUCTURE_2ouc|  PDB=2ouc  |  SCENE=  }}
+==Crystal structure of the MAP kinase binding domain of MKP5==
+<StructureSection load='2ouc' size='340' side='right'caption='[[2ouc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-===Crystal structure of the MAP kinase binding domain of MKP5===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2ouc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OUC FirstGlance]. <br>
-{{ABSTRACT_PUBMED_17400920}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ouc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ouc OCA], [https://pdbe.org/2ouc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ouc RCSB], [https://www.ebi.ac.uk/pdbsum/2ouc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ouc ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[2ouc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUC OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/DUS10_HUMAN DUS10_HUMAN] Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.<ref>PMID:22375048</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ou/2ouc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ouc ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[MAP kinase phosphatase|MAP kinase phosphatase]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:017400920</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Tao, X.]]
+[[Category: Large Structures]]
-[[Category: Tong, L.]]
+[[Category: Tao X]]
-[[Category: Hydrolase]]
+[[Category: Tong L]]
-[[Category: Rhodanese fold]]