3pjp: Difference between revisions

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[[Image:3pjp.png|left|200px]]


{{STRUCTURE_3pjp|  PDB=3pjp  |  SCENE=  }}
==A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain(CTD)==
 
<StructureSection load='3pjp' size='340' side='right'caption='[[3pjp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain(CTD)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3pjp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3or8 3or8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJP FirstGlance]. <br>
{{ABSTRACT_PUBMED_20926372}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pjp OCA], [https://pdbe.org/3pjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pjp RCSB], [https://www.ebi.ac.uk/pdbsum/3pjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pjp ProSAT]</span></td></tr>
[[3pjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3or8 3or8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJP OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPT6_CANGA SPT6_CANGA] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).


==See Also==
==See Also==
*[[Elongation factor|Elongation factor]]
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020926372</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Candida glabrata]]
[[Category: Cramer P]]
[[Category: Cramer, P.]]
[[Category: Dengl S]]
[[Category: Dengl, S.]]
[[Category: Lariviere L]]
[[Category: Lariviere, L.]]
[[Category: Mayer A]]
[[Category: Mayer, A.]]
[[Category: Sun M]]
[[Category: Sun, M.]]
[[Category: Ctd binding]]
[[Category: Nucleus]]
[[Category: Sh2]]
[[Category: Transcription]]
[[Category: Transcription elongation]]

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