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[[Image:3aed.png|left|200px]]


{{STRUCTURE_3aed|  PDB=3aed  |  SCENE=  }}
==Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-phenyl-benzamide==
 
<StructureSection load='3aed' size='340' side='right'caption='[[3aed]], [[Resolution|resolution]] 3.52&Aring;' scene=''>
===Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-phenyl-benzamide===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3aed]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AED FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.52&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOL:2-IODO-N-PHENYLBENZAMIDE'>BOL</scene>, <scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
[[3aed]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AED OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aed OCA], [https://pdbe.org/3aed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aed RCSB], [https://www.ebi.ac.uk/pdbsum/3aed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aed ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDHB_PIG SDHB_PIG] Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


==See Also==
==See Also==
*[[Succinate Dehydrogenase|Succinate Dehydrogenase]]
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Harada, S.]]
[[Category: Harada S]]
[[Category: Honma, T.]]
[[Category: Honma T]]
[[Category: Inaoka, D K.]]
[[Category: Inaoka DK]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kido, Y.]]
[[Category: Kido Y]]
[[Category: Kita, K.]]
[[Category: Kita K]]
[[Category: Mao, J.]]
[[Category: Mao J]]
[[Category: Matsuoka, S.]]
[[Category: Matsuoka S]]
[[Category: Omori, J.]]
[[Category: Omori J]]
[[Category: Osanai, A.]]
[[Category: Osanai A]]
[[Category: Sakamoto, K.]]
[[Category: Sakamoto K]]
[[Category: Sasaki, T.]]
[[Category: Sasaki T]]
[[Category: Shindo, M.]]
[[Category: Shindo M]]
[[Category: Tanaka, A.]]
[[Category: Tanaka A]]
[[Category: Electron transport]]
[[Category: Fad-binding protein]]
[[Category: Heme]]
[[Category: Inhibitor]]
[[Category: Iron]]
[[Category: Iron-sulfur]]
[[Category: Metal-binding]]
[[Category: Mitochondrion]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Respiratory complex ii]]
[[Category: Transit peptide]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Tricarboxylic acid cycle]]

Latest revision as of 04:35, 21 November 2024

Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-phenyl-benzamideCrystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-phenyl-benzamide

Structural highlights

3aed is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.52Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SDHB_PIG Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

See Also

3aed, resolution 3.52Å

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