2ypn: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2ypn.png|left|200px]]
-{{STRUCTURE_2ypn|  PDB=2ypn  |  SCENE=  }}
+==Hydroxymethylbilane synthase==
+<StructureSection load='2ypn' size='340' side='right'caption='[[2ypn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-===Hydroxymethylbilane synthase===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2ypn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YPN FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene></td></tr>
-[[2ypn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPN OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ypn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ypn OCA], [https://pdbe.org/2ypn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ypn RCSB], [https://www.ebi.ac.uk/pdbsum/2ypn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ypn ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HEM3_ECOLI HEM3_ECOLI] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/2ypn_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ypn ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Porphobilinogen Deaminase|Porphobilinogen Deaminase]]
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Hydroxymethylbilane synthase]]
+[[Category: Large Structures]]
-[[Category: Campbell, J W.]]
+[[Category: Campbell JW]]
-[[Category: Habash, J.]]
+[[Category: Habash J]]
-[[Category: Haedener, A.]]
+[[Category: Haedener A]]
-[[Category: Hao, Q.]]
+[[Category: Hao Q]]
-[[Category: Helliwell, J R.]]
+[[Category: Helliwell JR]]
-[[Category: Nieh, Y P.]]
+[[Category: Nieh YP]]
-[[Category: Raftery, J.]]
+[[Category: Raftery J]]
-[[Category: Schotte, F.]]
+[[Category: Schotte F]]
-[[Category: Ursby, T.]]
+[[Category: Ursby T]]
-[[Category: Weisgerber, S.]]
+[[Category: Weisgerber S]]
-[[Category: Wulff, M.]]
+[[Category: Wulff M]]
-[[Category: All alpha/beta]]
-[[Category: Biosynthesis of linear tetrapyrrole]]
-[[Category: Transferase]]