1mkj: Difference between revisions

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-[[Image:1mkj.png|left|200px]]
-{{STRUCTURE_1mkj|  PDB=1mkj  |  SCENE=  }}
+==Human Kinesin Motor Domain With Docked Neck Linker==
+<StructureSection load='1mkj' size='340' side='right'caption='[[1mkj]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-===Human Kinesin Motor Domain With Docked Neck Linker===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1mkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MKJ FirstGlance]. <br>
-{{ABSTRACT_PUBMED_12368902}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mkj OCA], [https://pdbe.org/1mkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mkj RCSB], [https://www.ebi.ac.uk/pdbsum/1mkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mkj ProSAT]</span></td></tr>
-[[1mkj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKJ OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KINH_HUMAN KINH_HUMAN] Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mkj_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mkj ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Kinesin|Kinesin]]
+*[[Kinesin 3D Structures|Kinesin 3D Structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:012368902</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Budny, M J.]]
+[[Category: Large Structures]]
-[[Category: Cooke, R.]]
+[[Category: Budny MJ]]
-[[Category: Fletterick, R.]]
+[[Category: Cooke R]]
-[[Category: Naber, N.]]
+[[Category: Fletterick R]]
-[[Category: Rice, S.]]
+[[Category: Naber N]]
-[[Category: Sindelar, C V.]]
+[[Category: Rice S]]
-[[Category: Atpase]]
+[[Category: Sindelar CV]]
-[[Category: Microtubule]]
-[[Category: Motor protein]]
-[[Category: Myosin]]
-[[Category: Neck linker]]
-[[Category: Relay helix]]
-[[Category: Switch ii]]
-[[Category: Transport protein]]