3sbg: Difference between revisions

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-[[Image:3sbg.png|left|200px]]
-{{STRUCTURE_3sbg|  PDB=3sbg  |  SCENE=  }}
+==Crystal structure of a Prp8 C-terminal fragment==
+<StructureSection load='3sbg' size='340' side='right'caption='[[3sbg]], [[Resolution|resolution]] 3.28&Aring;' scene=''>
-===Crystal structure of a Prp8 C-terminal fragment===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBG FirstGlance]. <br>
-{{ABSTRACT_PUBMED_21764848}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.28&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [https://pdbe.org/3sbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [https://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
 ==See Also==
-*[[Pre-mRNA-splicing factor|Pre-mRNA-splicing factor]]
+*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
-*[[Prp8|Prp8]]
+== References ==
+<references/>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:021764848</ref><references group="xtra"/>
+</StructureSection>
-[[Category: Saccharomyces cerevisiae]]
+[[Category: Large Structures]]
-[[Category: Holton, N.]]
+[[Category: Saccharomyces cerevisiae S288C]]
-[[Category: Santos, K.]]
+[[Category: Holton N]]
-[[Category: Wahl, M C.]]
+[[Category: Santos K]]
-[[Category: Weber, G.]]
+[[Category: Wahl MC]]
-[[Category: Jab1/mpn domain]]
+[[Category: Weber G]]
-[[Category: Prp8p]]
-[[Category: Rnaseh domain]]
-[[Category: Splicing]]