1m7o: Difference between revisions

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-[[Image:1m7o.png|left|200px]]
-{{STRUCTURE_1m7o|  PDB=1m7o  |  SCENE=  }}
+==Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog 3-phosphoglycerate (3PG)==
+<StructureSection load='1m7o' size='340' side='right'caption='[[1m7o]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-===Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog 3-phosphoglycerate (3PG)===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1m7o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7O FirstGlance]. <br>
-{{ABSTRACT_PUBMED_12454456}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7o OCA], [https://pdbe.org/1m7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7o RCSB], [https://www.ebi.ac.uk/pdbsum/1m7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7o ProSAT]</span></td></tr>
-[[1m7o]] is a 2 chain structure of [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7O OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TPIS_PLAFA TPIS_PLAFA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7o_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m7o ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
+*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:012454456</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Plasmodium falciparum]]
-[[Category: Triose-phosphate isomerase]]
+[[Category: Balaram H]]
-[[Category: Balaram, H.]]
+[[Category: Balaram P]]
-[[Category: Balaram, P.]]
+[[Category: Murthy MRN]]
-[[Category: Murthy, M R.N.]]
+[[Category: Parthasarathy S]]
-[[Category: Parthasarathy, S.]]
-[[Category: Beta-alpha barrel]]
-[[Category: Enzyme-inhibitor complex]]
-[[Category: Isomerase]]
-[[Category: Tim barrel]]