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[[Image:1j1s.gif|left|200px]]<br /><applet load="1j1s" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1j1s, resolution 2.00&Aring;" />
'''Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin'''<br />


==About this Structure==
==Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin==
1J1S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phytolacca_americana Phytolacca americana] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=FMP:'>FMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1S OCA].  
<StructureSection load='1j1s' size='340' side='right'caption='[[1j1s]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1j1s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phytolacca_americana Phytolacca americana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J1S FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMP:FORMYCIN-5-MONOPHOSPHATE'>FMP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1s OCA], [https://pdbe.org/1j1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j1s RCSB], [https://www.ebi.ac.uk/pdbsum/1j1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j1s ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RIPS_PHYAM RIPS_PHYAM] Inhibits viral infection of plants, and protein synthesis in vitro.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/1j1s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j1s ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Phytolacca americana]]
[[Category: Phytolacca americana]]
[[Category: Single protein]]
[[Category: Fujii H]]
[[Category: rRNA N-glycosylase]]
[[Category: Hidaka A]]
[[Category: Fujii, H.]]
[[Category: Honjo E]]
[[Category: Hidaka, A.]]
[[Category: Kurokawa H]]
[[Category: Honjo, E.]]
[[Category: Mikami B]]
[[Category: Kurokawa, H.]]
[[Category: Monzingo AF]]
[[Category: Mikami, B.]]
[[Category: Motoshima H]]
[[Category: Monzingo, A F.]]
[[Category: Robertus JD]]
[[Category: Motoshima, H.]]
[[Category: Sato E]]
[[Category: Robertus, J D.]]
[[Category: Watanabe K]]
[[Category: Sato, E.]]
[[Category: Watanabe, K.]]
[[Category: FMP]]
[[Category: NAG]]
[[Category: n-glycosidase]]
[[Category: pokeweed antiviral protein]]
[[Category: ribosome-inactivating protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:18:05 2008''

Latest revision as of 11:32, 6 November 2024

Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with FormycinPokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin

Structural highlights

1j1s is a 1 chain structure with sequence from Phytolacca americana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RIPS_PHYAM Inhibits viral infection of plants, and protein synthesis in vitro.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1j1s, resolution 2.00Å

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OCA
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