2ex5: Difference between revisions

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-[[Image:2ex5.png|left|200px]]
-{{STRUCTURE_2ex5|  PDB=2ex5  |  SCENE=  }}
+==Group I Intron-encoded Homing Endonuclease I-CeuI Complexed With DNA==
+<StructureSection load='2ex5' size='340' side='right'caption='[[2ex5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-===Group I Intron-encoded Homing Endonuclease I-CeuI Complexed With DNA===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2ex5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_moewusii Chlamydomonas moewusii] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EX5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EX5 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_16698548}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ex5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ex5 OCA], [https://pdbe.org/2ex5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ex5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ex5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ex5 ProSAT]</span></td></tr>
-[[2ex5]] is a 4 chain structure of [[Endonuclease]] with sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_moewusii Chlamydomonas moewusii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EX5 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DNE1_CHLMO DNE1_CHLMO] Endonuclease involved in intron homing. Recognizes a degenerate sequence of 17-19 bp to produce a staggered cut 5 bp downstream from the CeLSU.5 intron insertion site.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/2ex5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ex5 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Endonuclease|Endonuclease]]
+*[[Endonuclease 3D structures|Endonuclease 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:016698548</ref><references group="xtra"/>
 [[Category: Chlamydomonas moewusii]]
-[[Category: Spiegel, P C.]]
+[[Category: Large Structures]]
-[[Category: Stoddard, B L.]]
+[[Category: Synthetic construct]]
-[[Category: Homing endonuclease]]
+[[Category: Spiegel PC]]
-[[Category: Homodimer]]
+[[Category: Stoddard BL]]
-[[Category: Hydrolase-dna complex]]
-[[Category: Laglidadg]]
-[[Category: Protein-dna complex]]