2phm: Difference between revisions

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-[[Image:2phm.png|left|200px]]
-{{STRUCTURE_2phm|  PDB=2phm  |  SCENE=  }}
+==STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED==
+<StructureSection load='2phm' size='340' side='right'caption='[[2phm]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-===STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2phm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PHM FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10331871}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2phm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phm OCA], [https://pdbe.org/2phm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2phm RCSB], [https://www.ebi.ac.uk/pdbsum/2phm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2phm ProSAT]</span></td></tr>
-[[2phm]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHM OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PH4H_RAT PH4H_RAT]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phm_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2phm ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]]
+*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:010331871</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Phenylalanine 4-monooxygenase]]
 [[Category: Rattus norvegicus]]
-[[Category: Cotton, R G.]]
+[[Category: Cotton RG]]
-[[Category: House, C M.]]
+[[Category: House CM]]
-[[Category: Jennings, I G.]]
+[[Category: Jennings IG]]
-[[Category: Kemp, B E.]]
+[[Category: Kemp BE]]
-[[Category: Kobe, B.]]
+[[Category: Kobe B]]
-[[Category: Michell, B J.]]
+[[Category: Michell BJ]]
-[[Category: Allosteric regulation]]
-[[Category: Aromatic amino acid hydroxylase]]
-[[Category: Intrasteric regulation]]
-[[Category: Oxidoreductase]]
-[[Category: Phenylalanine hydroxylase]]
-[[Category: Phosphorylation]]