3b7k: Difference between revisions

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-[[Image:3b7k.png|left|200px]]
-{{STRUCTURE_3b7k|  PDB=3b7k  |  SCENE=  }}
+==Human Acyl-coenzyme A thioesterase 12==
+<StructureSection load='3b7k' size='340' side='right'caption='[[3b7k]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-===Human Acyl-coenzyme A thioesterase 12===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3b7k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B7K FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
-[[3b7k]] is a 3 chain structure of [[Thioesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7K OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7k OCA], [https://pdbe.org/3b7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b7k RCSB], [https://www.ebi.ac.uk/pdbsum/3b7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b7k ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACO12_HUMAN ACO12_HUMAN] Hydrolyzes acetyl-CoA to acetate and CoA.<ref>PMID:16951743</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/3b7k_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b7k ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Thioesterase|Thioesterase]]
+*[[Thioesterase 3D structures|Thioesterase 3D structures]]
-[[Category: Acetyl-CoA hydrolase]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Large Structures]]
-[[Category: Berg, S Van Den.]]
+[[Category: Arrowsmith CH]]
-[[Category: Berglund, H.]]
+[[Category: Berglund H]]
-[[Category: Busam, R D.]]
+[[Category: Busam RD]]
-[[Category: Collins, R.]]
+[[Category: Collins R]]
-[[Category: Dahlgren, L G.]]
+[[Category: Dahlgren LG]]
-[[Category: Edwards, A M.]]
+[[Category: Edwards AM]]
-[[Category: Flodin, S.]]
+[[Category: Flodin S]]
-[[Category: Flores, A.]]
+[[Category: Flores A]]
-[[Category: Graslund, S.]]
+[[Category: Graslund S]]
-[[Category: Hallberg, B M.]]
+[[Category: Hallberg BM]]
-[[Category: Hammarstrom, M.]]
+[[Category: Hammarstrom M]]
-[[Category: Herman, M D.]]
+[[Category: Herman MD]]
-[[Category: Johansson, A.]]
+[[Category: Johansson A]]
-[[Category: Johansson, I.]]
+[[Category: Johansson I]]
-[[Category: Kallas, A.]]
+[[Category: Kallas A]]
-[[Category: Karlberg, T.]]
+[[Category: Karlberg T]]
-[[Category: Kotenyova, T.]]
+[[Category: Kotenyova T]]
-[[Category: L., Svensson.]]
+[[Category: Lehtio L]]
-[[Category: Lehtio, L.]]
+[[Category: Moche M]]
-[[Category: Moche, M.]]
+[[Category: Nilsson ME]]
-[[Category: Nilsson, M E.]]
+[[Category: Nordlund P]]
-[[Category: Nordlund, P.]]
+[[Category: Nyman T]]
-[[Category: Nyman, T.]]
+[[Category: Persson C]]
-[[Category: Persson, C.]]
+[[Category: Sagemark J]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Sundstrom M]]
-[[Category: Sagemark, J.]]
+[[Category: Svensson L]]
-[[Category: Sundstrom, M.]]
+[[Category: Thorsell AG]]
-[[Category: Thorsell, A G.]]
+[[Category: Tresaugues L]]
-[[Category: Tresaugues, L.]]
+[[Category: Van Den Berg S]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt J]]
-[[Category: Welin, M.]]
+[[Category: Welin M]]
-[[Category: Fatty acid metabolism]]
-[[Category: Hotdog fold]]
-[[Category: Hydrolase]]
-[[Category: Lipid metabolism]]
-[[Category: Serine esterase]]
-[[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]