1bo6: Difference between revisions

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[[Image:1bo6.png|left|200px]]


{{STRUCTURE_1bo6|  PDB=1bo6  |  SCENE=  }}
==ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE==
 
<StructureSection load='1bo6' size='340' side='right'caption='[[1bo6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1bo6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BO6 FirstGlance]. <br>
{{ABSTRACT_PUBMED_9765259}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene>, <scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bo6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bo6 OCA], [https://pdbe.org/1bo6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bo6 RCSB], [https://www.ebi.ac.uk/pdbsum/1bo6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bo6 ProSAT]</span></td></tr>
[[1bo6]] is a 2 chain structure of [[Sulfotransferase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BO6 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/ST1E1_MOUSE ST1E1_MOUSE] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/1bo6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bo6 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Sulfotransferase|Sulfotransferase]]
*[[Sulfotransferase 3D structures|Sulfotransferase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:009765259</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Estrone sulfotransferase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Kakuta, Y.]]
[[Category: Kakuta Y]]
[[Category: Negishi, M.]]
[[Category: Negishi M]]
[[Category: Pedersen, L C.]]
[[Category: Pedersen LC]]
[[Category: Pap]]
[[Category: Sulfonation]]
[[Category: Sulfotransferase]]
[[Category: Transferase]]
[[Category: Vanadate]]

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