3ut9: Difference between revisions

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[[Image:3ut9.png|left|200px]]


{{STRUCTURE_3ut9|  PDB=3ut9  |  SCENE=  }}
==Crystal Structure of Nucleosome Core Particle Assembled with a Palindromic Widom '601' Derivative (NCP-601L)==
 
<StructureSection load='3ut9' size='340' side='right'caption='[[3ut9]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal Structure of Nucleosome Core Particle Assembled with a Palindromic Widom '601' Derivative (NCP-601L)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ut9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UT9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22453276}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ut9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ut9 OCA], [https://pdbe.org/3ut9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ut9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ut9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ut9 ProSAT]</span></td></tr>
[[3ut9]] is a 10 chain structure of [[Histone]] with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UT9 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


==See Also==
==See Also==
*[[Histone|Histone]]
*[[Histone 3D structures|Histone 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022453276</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Xenopus laevis]]
[[Category: Xenopus laevis]]
[[Category: Chua, E Y.D.]]
[[Category: Chua EYD]]
[[Category: Davey, C A.]]
[[Category: Davey CA]]
[[Category: Davey, G E.]]
[[Category: Davey GE]]
[[Category: Vasudevan, D.]]
[[Category: Vasudevan D]]
[[Category: Wu, B.]]
[[Category: Wu B]]
[[Category: 601-sequence dna]]
[[Category: Ncp]]
[[Category: Nucleosome core particle]]
[[Category: Structural protein-dna complex]]

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