1iku: Difference between revisions

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[[Image:1iku.png|left|200px]]


{{STRUCTURE_1iku|  PDB=1iku  |  SCENE=  }}
==myristoylated recoverin in the calcium-free state, NMR, 22 structures==
 
<StructureSection load='1iku' size='340' side='right'caption='[[1iku]]' scene=''>
===myristoylated recoverin in the calcium-free state, NMR, 22 structures===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1iku]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IKU FirstGlance]. <br>
{{ABSTRACT_PUBMED_7630423}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iku OCA], [https://pdbe.org/1iku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iku RCSB], [https://www.ebi.ac.uk/pdbsum/1iku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iku ProSAT]</span></td></tr>
[[1iku]] is a 1 chain structure of [[Recoverin%2C a calcium-activated myristoyl switch]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IKU OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RECO_BOVIN RECO_BOVIN] Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.<ref>PMID:8097896</ref> <ref>PMID:8392055</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/1iku_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iku ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Recoverin%2C a calcium-activated myristoyl switch|Recoverin%2C a calcium-activated myristoyl switch]]
*[[Recoverin%2C a calcium-activated myristoyl switch|Recoverin%2C a calcium-activated myristoyl switch]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:007630423</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Ames, J B.]]
[[Category: Large Structures]]
[[Category: Harvey, T S.]]
[[Category: Ames JB]]
[[Category: Ikura, M.]]
[[Category: Harvey TS]]
[[Category: Stryer, L.]]
[[Category: Ikura M]]
[[Category: Tanaka, T.]]
[[Category: Stryer L]]
[[Category: Calcium-binding protein]]
[[Category: Tanaka T]]
[[Category: Calcium-myristoyl switch]]
[[Category: Calcuim-binding protein]]

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