2gf0: Difference between revisions

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[[Image:2gf0.png|left|200px]]


{{STRUCTURE_2gf0|  PDB=2gf0  |  SCENE=  }}
==The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state==
 
<StructureSection load='2gf0' size='340' side='right'caption='[[2gf0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[2gf0]] is a 4 chain structure of [[GTP-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [https://pdbe.org/2gf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf0 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[GTP-binding protein|GTP-binding protein]]
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Large Structures]]
[[Category: Bray, J.]]
[[Category: Arrowsmith C]]
[[Category: Delft, F von.]]
[[Category: Bray J]]
[[Category: Doyle, D.]]
[[Category: Doyle D]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Elkins, J.]]
[[Category: Elkins J]]
[[Category: Fedorov, O.]]
[[Category: Fedorov O]]
[[Category: Gileadi, O.]]
[[Category: Gileadi O]]
[[Category: Niesen, F E.]]
[[Category: Niesen FE]]
[[Category: Papagrigoriou, E.]]
[[Category: Papagrigoriou E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Salah E]]
[[Category: Salah, E.]]
[[Category: Schoch G]]
[[Category: Schoch, G.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Turnbull AP]]
[[Category: Turnbull, A P.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Wen-Hwa L]]
[[Category: Wen-Hwa, L.]]
[[Category: Yang X]]
[[Category: Yang, X.]]
[[Category: Von Delft F]]
[[Category: Dira]]
[[Category: Gdp/gtp binding]]
[[Category: Gtp hydrolysis]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Transport protein]]

Latest revision as of 12:39, 30 August 2023

The crystal structure of the human DiRas1 GTPase in the inactive GDP bound stateThe crystal structure of the human DiRas1 GTPase in the inactive GDP bound state

Structural highlights

2gf0 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DIRA1_HUMAN Displays low GTPase activity and exist predominantly in the GTP-bound form.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2gf0, resolution 1.90Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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