2axx: Difference between revisions

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-[[Image:2axx.png|left|200px]]
-{{STRUCTURE_2axx|  PDB=2axx  |  SCENE=  }}
+==THE SOLUTION STRUCTURE OF OXIDIZED RAT MICROSOMAL CYTOCHROME B5, NMR, 21 STRUCTURES==
+<StructureSection load='2axx' size='340' side='right'caption='[[2axx]]' scene=''>
-===THE SOLUTION STRUCTURE OF OXIDIZED RAT MICROSOMAL CYTOCHROME B5, NMR, 21 STRUCTURES===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2axx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AXX FirstGlance]. <br>
-{{ABSTRACT_PUBMED_9425037}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2axx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2axx OCA], [https://pdbe.org/2axx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2axx RCSB], [https://www.ebi.ac.uk/pdbsum/2axx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2axx ProSAT]</span></td></tr>
-[[2axx]] is a 1 chain structure of [[Cytochrome b5]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AXX OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CYB5_RAT CYB5_RAT] Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. It is also involved in several steps of the sterol biosynthesis pathway, particularly in the C-6 double bond introduction during the C-6 desaturation.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ax/2axx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2axx ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Cytochrome b5|Cytochrome b5]]
+*[[Cytochrome b5 3D structures|Cytochrome b5 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:009425037</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Arnesano, F.]]
+[[Category: Arnesano F]]
-[[Category: Banci, L.]]
+[[Category: Banci L]]
-[[Category: Bertini, I.]]
+[[Category: Bertini I]]
-[[Category: Felli, I C.]]
+[[Category: Felli IC]]
-[[Category: Cytochrome b5]]
-[[Category: Electron transfer]]
-[[Category: Electron transport]]
-[[Category: Paramagnetic nmr]]
-[[Category: Protein recognition]]
-[[Category: Solution structure]]