3fvp: Difference between revisions

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-[[Image:3fvp.png|left|200px]]
-{{STRUCTURE_3fvp|  PDB=3fvp  |  SCENE=  }}
+==Thermolysin inhibition==
+<StructureSection load='3fvp' size='340' side='right'caption='[[3fvp]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
-===Thermolysin inhibition===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3fvp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FVP FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UB2:N-[(S)-({[(BENZYLOXY)CARBONYL]AMINO}METHYL)(HYDROXY)PHOSPHORYL]-L-ALANYL-L-LEUCINE'>UB2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[3fvp]] is a 1 chain structure of [[Thermolysin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVP OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvp OCA], [https://pdbe.org/3fvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fvp RCSB], [https://www.ebi.ac.uk/pdbsum/3fvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fvp ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Thermolysin|Thermolysin]]
+*[[Thermolysin 3D structures|Thermolysin 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Bacillus thermoproteolyticus]]
-[[Category: Thermolysin]]
+[[Category: Large Structures]]
-[[Category: Biela, A.]]
+[[Category: Biela A]]
-[[Category: Englert, L.]]
+[[Category: Englert L]]
-[[Category: Heine, A.]]
+[[Category: Heine A]]
-[[Category: Klebe, G.]]
+[[Category: Klebe G]]
-[[Category: Hydrolase]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Metal-binding]]
-[[Category: Metalloprotease]]
-[[Category: Protease]]
-[[Category: Protease phosphonamidate inhibitor]]