1g6r: Difference between revisions

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[[Image:1g6r.png|left|200px]]


{{STRUCTURE_1g6r|  PDB=1g6r  |  SCENE=  }}
==A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX==
 
<StructureSection load='1g6r' size='340' side='right'caption='[[1g6r]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
===A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1g6r]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G6R FirstGlance]. <br>
{{ABSTRACT_PUBMED_10755612}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g6r OCA], [https://pdbe.org/1g6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g6r RCSB], [https://www.ebi.ac.uk/pdbsum/1g6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g6r ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1g6r]] is a 10 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G6R OCA].  
== Function ==
[https://www.uniprot.org/uniprot/TVA1_MOUSE TVA1_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/1g6r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g6r ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[Major histocompatibility complex|Major histocompatibility complex]]
*[[MHC 3D structures|MHC 3D structures]]
 
*[[MHC I 3D structures|MHC I 3D structures]]
==Reference==
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
<ref group="xtra">PMID:010755612</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Apostolopoulos, V.]]
[[Category: Apostolopoulos V]]
[[Category: Degano, M.]]
[[Category: Degano M]]
[[Category: Garcia, K C.]]
[[Category: Garcia KC]]
[[Category: Rudolph, M G.]]
[[Category: Rudolph MG]]
[[Category: Teyton, L.]]
[[Category: Teyton L]]
[[Category: Wilson, I A.]]
[[Category: Wilson IA]]
[[Category: Immune system]]
[[Category: Major histocompatibility complex]]
[[Category: Superagonist]]
[[Category: T cell antigen receptor]]

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