1lfk: Difference between revisions

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[[Image:1lfk.png|left|200px]]


{{STRUCTURE_1lfk|  PDB=1lfk  |  SCENE=  }}
==Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis==
 
<StructureSection load='1lfk' size='340' side='right'caption='[[1lfk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
===Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1lfk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LFK FirstGlance]. <br>
{{ABSTRACT_PUBMED_12207020}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lfk OCA], [https://pdbe.org/1lfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lfk RCSB], [https://www.ebi.ac.uk/pdbsum/1lfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lfk ProSAT]</span></td></tr>
[[1lfk]] is a 1 chain structure of [[Cytochrome P450]] with sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LFK OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/C5B3_AMYOR C5B3_AMYOR]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lf/1lfk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lfk ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cytochrome P450|Cytochrome P450]]
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:012207020</ref><references group="xtra"/>
[[Category: Amycolatopsis orientalis]]
[[Category: Amycolatopsis orientalis]]
[[Category: Pylypenko, O.]]
[[Category: Large Structures]]
[[Category: Robinson, J A.]]
[[Category: Pylypenko O]]
[[Category: Schlichting, I.]]
[[Category: Robinson JA]]
[[Category: Vitali, F.]]
[[Category: Schlichting I]]
[[Category: Vrijbloed, J W.]]
[[Category: Vitali F]]
[[Category: Zerbe, K.]]
[[Category: Vrijbloed JW]]
[[Category: Zhang, W.]]
[[Category: Zerbe K]]
[[Category: Oxidative phenol coupling reaction p450 vancomycin]]
[[Category: Zhang W]]
[[Category: Oxidoreductase]]

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