1mws: Difference between revisions

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[[Image:1mws.png|left|200px]]


{{STRUCTURE_1mws|  PDB=1mws  |  SCENE=  }}
==Structure of nitrocefin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.00 A resolution.==
 
<StructureSection load='1mws' size='340' side='right'caption='[[1mws]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===Structure of nitrocefin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.00 A resolution.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1mws]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MWS FirstGlance]. <br>
{{ABSTRACT_PUBMED_12389036}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NC1:NITROCEFIN+ACYL-SERINE'>NC1</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mws OCA], [https://pdbe.org/1mws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mws RCSB], [https://www.ebi.ac.uk/pdbsum/1mws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mws ProSAT]</span></td></tr>
[[1mws]] is a 2 chain structure of [[Penicillin-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWS OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q93IC2_STAAU Q93IC2_STAAU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/1mws_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mws ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Penicillin-binding protein|Penicillin-binding protein]]
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:012389036</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Lim, D C.]]
[[Category: Lim DC]]
[[Category: Strynadka, N C.J.]]
[[Category: Strynadka NCJ]]
[[Category: Beta-lactam]]
[[Category: Biosynthetic protein]]
[[Category: D-carboxypeptidase]]
[[Category: D-transpeptidase]]
[[Category: Nitrocefin]]
[[Category: Penicillin binding protein]]

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