1col: Difference between revisions

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-[[Image:1col.png|left|200px]]
-{{STRUCTURE_1col|  PDB=1col  |  SCENE=  }}
+==REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION==
+<StructureSection load='1col' size='340' side='right'caption='[[1col]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-===REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1col]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1COL FirstGlance]. <br>
-{{ABSTRACT_PUBMED_1373773}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1col FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1col OCA], [https://pdbe.org/1col PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1col RCSB], [https://www.ebi.ac.uk/pdbsum/1col PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1col ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1col]] is a 2 chain structure of [[Colicin]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COL OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/CEA_ECOLX CEA_ECOLX] This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.<ref>PMID:2434951</ref>   Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.<ref>PMID:2434951</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1col_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1col ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Colicin|Colicin]]
+*[[Colicin 3D structures|Colicin 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:001373773</ref><ref group="xtra">PMID:011170211</ref><ref group="xtra">PMID:012215419</ref><ref group="xtra">PMID:014695246</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Parker, M W.]]
+[[Category: Large Structures]]
-[[Category: Pattus, F.]]
+[[Category: Parker MW]]
-[[Category: Postma, J P.M.]]
+[[Category: Pattus F]]
-[[Category: Tsernoglou, D.]]
+[[Category: Postma JPM]]
-[[Category: Tucker, A D.]]
+[[Category: Tsernoglou D]]
-[[Category: Antibacterial protein]]
+[[Category: Tucker AD]]