1dai: Difference between revisions

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-[[Image:1dai.png|left|200px]]
-{{STRUCTURE_1dai|  PDB=1dai  |  SCENE=  }}
+==DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID==
+<StructureSection load='1dai' size='340' side='right'caption='[[1dai]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
-===DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1dai]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DAI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DAI FirstGlance]. <br>
-{{ABSTRACT_PUBMED_7669756}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSD:7-(CARBOXYAMINO)-8-AMINO-NONANOIC+ACID'>DSD</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dai FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dai OCA], [https://pdbe.org/1dai PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dai RCSB], [https://www.ebi.ac.uk/pdbsum/1dai PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dai ProSAT]</span></td></tr>
-[[1dai]] is a 1 chain structure of [[Dethiobiotin synthetase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DAI OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BIOD1_ECOLI BIOD1_ECOLI] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring. Only CTP can partially replace ATP while diaminobiotin is only 37% as effective as 7,8-diaminopelargonic acid.<ref>PMID:4892372</ref> <ref>PMID:4921568</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/da/1dai_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dai ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Dethiobiotin synthetase|Dethiobiotin synthetase]]
+*[[Dethiobiotin synthetase 3D structures|Dethiobiotin synthetase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:007669756</ref><references group="xtra"/>
+__TOC__
-[[Category: Dethiobiotin synthase]]
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Huang, W.]]
+[[Category: Large Structures]]
-[[Category: Jia, J.]]
+[[Category: Huang W]]
-[[Category: Lindqvist, Y.]]
+[[Category: Jia J]]
-[[Category: Schneider, G.]]
+[[Category: Lindqvist Y]]
-[[Category: Atp-binding]]
+[[Category: Schneider G]]
-[[Category: Biotin biosynthesis]]
-[[Category: Ligase]]
-[[Category: Magnesium]]