3g9c: Difference between revisions

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-[[Image:3g9c.png|left|200px]]
-{{STRUCTURE_3g9c|  PDB=3g9c  |  SCENE=  }}
+==Crystal structure of the product Bacillus anthracis glmS ribozyme==
+<StructureSection load='3g9c' size='340' side='right'caption='[[3g9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-===Crystal structure of the product Bacillus anthracis glmS ribozyme===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3g9c]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G9C FirstGlance]. <br>
-{{ABSTRACT_PUBMED_19228039}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLP:GLUCOSAMINE+6-PHOSPHATE'>GLP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9c OCA], [https://pdbe.org/3g9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g9c RCSB], [https://www.ebi.ac.uk/pdbsum/3g9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g9c ProSAT]</span></td></tr>
-[[3g9c]] is a 12 chain structure of [[Nucleoprotein]] and [[Ribozyme]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G9C OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/3g9c_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g9c ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Nucleoprotein|Nucleoprotein]]
+*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
-*[[Ribozyme|Ribozyme]]
+*[[Ribozyme 3D structures|Ribozyme 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:019228039</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Cochrane, J C.]]
+[[Category: Large Structures]]
-[[Category: Lipchock, S V.]]
+[[Category: Synthetic construct]]
-[[Category: Smith, K D.]]
+[[Category: Cochrane JC]]
-[[Category: Strobel, S A.]]
+[[Category: Lipchock SV]]
-[[Category: Catalytic rna]]
+[[Category: Smith KD]]
-[[Category: Mrna processing]]
+[[Category: Strobel SA]]
-[[Category: Mrna splicing]]
-[[Category: Nucleus]]
-[[Category: Phosphoprotein]]
-[[Category: Ribonucleoprotein]]
-[[Category: Rna binding protein-rna complex]]
-[[Category: Rna-binding]]
-[[Category: Spliceosome]]