3da2: Difference between revisions

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[[Image:3da2.png|left|200px]]


{{STRUCTURE_3da2|  PDB=3da2  |  SCENE=  }}
==X-ray structure of human carbonic anhydrase 13 in complex with inhibitor==
 
<StructureSection load='3da2' size='340' side='right'caption='[[3da2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
===X-ray structure of human carbonic anhydrase 13 in complex with inhibitor===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3da2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DA2 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MD:N-(4-CHLOROBENZYL)-N-METHYLBENZENE-1,4-DISULFONAMIDE'>4MD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[3da2]] is a 2 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3da2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3da2 OCA], [https://pdbe.org/3da2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3da2 RCSB], [https://www.ebi.ac.uk/pdbsum/3da2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3da2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN] Reversible hydration of carbon dioxide.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/da/3da2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3da2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Carbonic anhydrase|Carbonic anhydrase]]
*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
[[Category: Carbonate dehydratase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Bray, J E.]]
[[Category: Bountra C]]
[[Category: Delft, F von.]]
[[Category: Bray JE]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Filippakopoulos, P.]]
[[Category: Filippakopoulos P]]
[[Category: King, O N.F.]]
[[Category: King ONF]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Picaud, S S.]]
[[Category: Picaud SS]]
[[Category: Pike, A C.W.]]
[[Category: Pike ACW]]
[[Category: Pilka, E S.]]
[[Category: Pilka ES]]
[[Category: Roos, A K.]]
[[Category: Roos AK]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Wikstrom M]]
[[Category: Wikstrom, M.]]
[[Category: Yue WW]]
[[Category: Yue, W W.]]
[[Category: Von Delft F]]
[[Category: Carbonic anhydrase]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Sulfonamide]]

Latest revision as of 15:43, 30 August 2023

X-ray structure of human carbonic anhydrase 13 in complex with inhibitorX-ray structure of human carbonic anhydrase 13 in complex with inhibitor

Structural highlights

3da2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAH13_HUMAN Reversible hydration of carbon dioxide.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3da2, resolution 2.05Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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