1v53: Difference between revisions

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-[[Image:1v53.png|left|200px]]
-{{STRUCTURE_1v53|  PDB=1v53  |  SCENE=  }}
+==The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans==
+<StructureSection load='1v53' size='340' side='right'caption='[[1v53]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
-===The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1v53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Weizmannia_coagulans Weizmannia coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V53 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v53 OCA], [https://pdbe.org/1v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v53 RCSB], [https://www.ebi.ac.uk/pdbsum/1v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v53 ProSAT]</span></td></tr>
-[[1v53]] is a 2 chain structure of [[Isopropylmalate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_coagulans Bacillus coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V53 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LEU3_WEICA LEU3_WEICA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v53_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v53 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
-[[Category: 3-isopropylmalate dehydrogenase]]
+__TOC__
-[[Category: Bacillus coagulans]]
+</StructureSection>
-[[Category: Fujita, K.]]
+[[Category: Large Structures]]
-[[Category: Minami, H.]]
+[[Category: Weizmannia coagulans]]
-[[Category: Mizui, R.]]
+[[Category: Fujita K]]
-[[Category: Nakamura, S.]]
+[[Category: Minami H]]
-[[Category: Sekiguchi, T.]]
+[[Category: Mizui R]]
-[[Category: Suzuki, K.]]
+[[Category: Nakamura S]]
-[[Category: Takenaka, A.]]
+[[Category: Sekiguchi T]]
-[[Category: Tsunoda, M.]]
+[[Category: Suzuki K]]
-[[Category: Tsuzaki, S.]]
+[[Category: Takenaka A]]
-[[Category: Bacillus coagulan]]
+[[Category: Tsunoda M]]
-[[Category: Homo dimer]]
+[[Category: Tsuzaki S]]
-[[Category: Ipmdh]]
-[[Category: Oxidoreductase]]
-[[Category: X-ray analysis]]