3spy: Difference between revisions

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[[Image:3spy.png|left|200px]]


{{STRUCTURE_3spy|  PDB=3spy  |  SCENE=  }}
==RB69 DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dA==
 
<StructureSection load='3spy' size='340' side='right'caption='[[3spy]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
===RB69 DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3spy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPY FirstGlance]. <br>
{{ABSTRACT_PUBMED_21923197}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UPC:2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]METHYL}PHOSPHORYL]URIDINE'>UPC</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spy OCA], [https://pdbe.org/3spy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spy RCSB], [https://www.ebi.ac.uk/pdbsum/3spy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spy ProSAT]</span></td></tr>
[[3spy]] is a 3 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPY OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021923197</ref><references group="xtra"/>
[[Category: Escherichia phage RB69]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Enterobacteria phage rb69]]
[[Category: Konigsberg WH]]
[[Category: Konigsberg, W H.]]
[[Category: Wang J]]
[[Category: Wang, J.]]
[[Category: Xia S]]
[[Category: Xia, S.]]
[[Category: Dupcpp]]
[[Category: Quadruple mutant]]
[[Category: Transferase-dna complex]]

Latest revision as of 12:54, 1 March 2024

RB69 DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dARB69 DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dA

Structural highlights

3spy is a 3 chain structure with sequence from Escherichia phage RB69. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.14Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPOL_BPR69 This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.

See Also

3spy, resolution 2.14Å

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