3rhd: Difference between revisions

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[[Image:3rhd.png|left|200px]]


{{STRUCTURE_3rhd|  PDB=3rhd  |  SCENE=  }}
==Crystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661 complexed with NADP==
 
<StructureSection load='3rhd' size='340' side='right'caption='[[3rhd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661 complexed with NADP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3rhd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RHD FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[3rhd]] is a 4 chain structure of [[Aldehyde dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RHD OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rhd OCA], [https://pdbe.org/3rhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rhd RCSB], [https://www.ebi.ac.uk/pdbsum/3rhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rhd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LADH_METJA LADH_METJA] Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP.


==See Also==
==See Also==
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
[[Category: Lactaldehyde dehydrogenase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Almo, S C.]]
[[Category: Almo SC]]
[[Category: Foti, R.]]
[[Category: Foti R]]
[[Category: Garrett, S.]]
[[Category: Garrett S]]
[[Category: Malashkevich, V N.]]
[[Category: Malashkevich VN]]
[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
[[Category: Seidel R]]
[[Category: Seidel, R.]]
[[Category: Toro R]]
[[Category: Toro, R.]]
[[Category: Dehydrogenase]]
[[Category: New york structural genomics research consortium]]
[[Category: New york structural genomix research consortium]]
[[Category: Nysgrc]]
[[Category: Oxidoreductase]]
[[Category: Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]

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