1avq: Difference between revisions

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[[Image:1avq.png|left|200px]]


{{STRUCTURE_1avq|  PDB=1avq  |  SCENE=  }}
==TOROIDAL STRUCTURE OF LAMBDA EXONUCLEASE DETERMINED AT 2.4 ANGSTROMS==
 
<StructureSection load='1avq' size='340' side='right'caption='[[1avq]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===TOROIDAL STRUCTURE OF LAMBDA EXONUCLEASE DETERMINED AT 2.4 ANGSTROMS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1avq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AVQ FirstGlance]. <br>
{{ABSTRACT_PUBMED_9295273}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1avq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1avq OCA], [https://pdbe.org/1avq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1avq RCSB], [https://www.ebi.ac.uk/pdbsum/1avq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1avq ProSAT]</span></td></tr>
[[1avq]] is a 3 chain structure of [[Exonuclease]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVQ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/EXO_LAMBD EXO_LAMBD] Facilitates phage DNA recombination through the double-strand break repair (DSBR) and single-strand annealing pathways. Also important for the late, rolling-circle mode of lambda DNA replication.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/av/1avq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1avq ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Exonuclease|Exonuclease]]
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
*[[Homology modeling servers|Homology modeling servers]]
__TOC__
 
</StructureSection>
==Reference==
[[Category: Escherichia virus Lambda]]
<ref group="xtra">PMID:009295273</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Enterobacteria phage lambda]]
[[Category: Kovall RA]]
[[Category: Kovall, R A.]]
[[Category: Matthews BW]]
[[Category: Matthews, B W.]]
[[Category: 5'-3' exonuclease]]
[[Category: Deoxyribonuclease]]
[[Category: Dna recombination and repair]]

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