2ht6: Difference between revisions

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-[[Image:2ht6.png|left|200px]]
-{{STRUCTURE_2ht6|  PDB=2ht6  |  SCENE=  }}
+==Crystal structure of Human Gem G-domain bound to GDP==
+<StructureSection load='2ht6' size='340' side='right'caption='[[2ht6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-===Crystal structure of Human Gem G-domain bound to GDP===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2ht6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HT6 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_17052716}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ht6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ht6 OCA], [https://pdbe.org/2ht6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ht6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ht6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ht6 ProSAT]</span></td></tr>
-[[2ht6]] is a 2 chain structure of [[GTP-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HT6 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GEM_HUMAN GEM_HUMAN] Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/2ht6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ht6 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[GTP-binding protein|GTP-binding protein]]
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:017052716</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Hirsch, J A.]]
+[[Category: Large Structures]]
-[[Category: Opatowsky, Y.]]
+[[Category: Hirsch JA]]
-[[Category: Signaling protein]]
+[[Category: Opatowsky Y]]
-[[Category: Small g-protein]]