1ngs: Difference between revisions

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-[[Image:1ngs.png|left|200px]]
-{{STRUCTURE_1ngs|  PDB=1ngs  |  SCENE=  }}
+==COMPLEX OF TRANSKETOLASE WITH THIAMIN DIPHOSPHATE, CA2+ AND ACCEPTOR SUBSTRATE ERYTHROSE-4-PHOSPHATE==
+<StructureSection load='1ngs' size='340' side='right'caption='[[1ngs]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-===COMPLEX OF TRANSKETOLASE WITH THIAMIN DIPHOSPHATE, CA2+ AND ACCEPTOR SUBSTRATE ERYTHROSE-4-PHOSPHATE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1ngs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NGS FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8999873}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=E4P:ERYTHOSE-4-PHOSPHATE'>E4P</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ngs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ngs OCA], [https://pdbe.org/1ngs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ngs RCSB], [https://www.ebi.ac.uk/pdbsum/1ngs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ngs ProSAT]</span></td></tr>
-[[1ngs]] is a 2 chain structure of [[Transketolase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NGS OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TKT1_YEAST TKT1_YEAST] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.<ref>PMID:8521838</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ng/1ngs_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ngs ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Transketolase|Transketolase]]
+*[[Transketolase 3D structures|Transketolase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:008999873</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Transketolase]]
+[[Category: Lindqvist Y]]
-[[Category: Lindqvist, Y.]]
+[[Category: Nilsson U]]
-[[Category: Nilsson, U.]]
+[[Category: Schneider G]]
-[[Category: Schneider, G.]]
-[[Category: Magnesium]]
-[[Category: Multigene family]]
-[[Category: Thiamine pyrophosphate]]
-[[Category: Transferase]]