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[[Image:1lnb.png|left|200px]]


{{STRUCTURE_1lnb|  PDB=1lnb  |  SCENE=  }}
==A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN==
 
<StructureSection load='1lnb' size='340' side='right'caption='[[1lnb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1lnb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LNB FirstGlance]. <br>
{{ABSTRACT_PUBMED_8535232}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lnb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lnb OCA], [https://pdbe.org/1lnb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lnb RCSB], [https://www.ebi.ac.uk/pdbsum/1lnb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lnb ProSAT]</span></td></tr>
[[1lnb]] is a 1 chain structure of [[Thermolysin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LNB OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/1lnb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lnb ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Thermolysin|Thermolysin]]
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008535232</ref><references group="xtra"/>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Thermolysin]]
[[Category: Large Structures]]
[[Category: Hausrath, A C.]]
[[Category: Hausrath AC]]
[[Category: Holland, D R.]]
[[Category: Holland DR]]
[[Category: Juers, D.]]
[[Category: Juers D]]
[[Category: Matthews, B W.]]
[[Category: Matthews BW]]

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