2v8z: Difference between revisions

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[[Image:2v8z.png|left|200px]]


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==Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12==
The line below this paragraph, containing "STRUCTURE_2v8z", creates the "Structure Box" on the page.
<StructureSection load='2v8z' size='340' side='right'caption='[[2v8z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2v8z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V8Z FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8z OCA], [https://pdbe.org/2v8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v8z RCSB], [https://www.ebi.ac.uk/pdbsum/2v8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8z ProSAT]</span></td></tr>
{{STRUCTURE_2v8z|  PDB=2v8z |  SCENE= }}
</table>
 
== Function ==
===CRYSTAL STRUCTURE OF YAGE, A PROPHAGE PROTEIN BELONGING TO THE DIHYDRODIPICOLINIC ACID SYNTHASE FAMILY FROM E. COLI K12===
[https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
[[2v8z]] is a 4 chain structure of [[Dihydrodipicolinate synthase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8Z OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8z_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v8z ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:018361457</ref><references group="xtra"/>
[[Category: Escherichia coli K-12]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Albeck, S.]]
[[Category: Albeck S]]
[[Category: Bourenkov, G.]]
[[Category: Bourenkov G]]
[[Category: Dym, O.]]
[[Category: Dym O]]
[[Category: Greenblatt, H M.]]
[[Category: Greenblatt HM]]
[[Category: Krishnaswamy, S.]]
[[Category: Krishnaswamy S]]
[[Category: Lamzin, V.]]
[[Category: Lamzin V]]
[[Category: Manicka, S.]]
[[Category: Manicka S]]
[[Category: Peleg, Y.]]
[[Category: Peleg Y]]
[[Category: Sussman, J L.]]
[[Category: Sussman JL]]
[[Category: Unger, T.]]
[[Category: Unger T]]
[[Category: Dhdp]]
[[Category: Lyase]]
[[Category: N-acetyl neuraminate lyase]]
[[Category: Nal]]

Latest revision as of 18:10, 13 December 2023

Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12

Structural highlights

2v8z is a 4 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YAGE_ECOLI Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2v8z, resolution 2.20Å

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OCA
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