3vtn: Difference between revisions

Latest revision as of 11:41, 20 March 2024

The crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MADThe crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MAD

Structural highlights

3vtn is a 1 chain structure with sequence from Escherichia virus Mu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.75Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BP45_BPMU Component of the baseplate that forms a central needlelike spike used to puncture the host cell membrane for tube insertion during virus entry. Probably involved in baseplate and tail assembly. Serves as the distal plug of tail tube channel and might regulate the process of the phage DNA and protein ejection into the host cell.^[1] ^[2]

References

↑ Suzuki H, Yamada S, Toyama Y, Takeda S. The C-terminal domain is sufficient for host-binding activity of the Mu phage tail-spike protein. Biochim Biophys Acta. 2010 Sep;1804(9):1738-42. doi:, 10.1016/j.bbapap.2010.05.003. Epub 2010 May 15. PMID:20478417 doi:http://dx.doi.org/10.1016/j.bbapap.2010.05.003
↑ Harada K, Yamashita E, Nakagawa A, Miyafusa T, Tsumoto K, Ueno T, Toyama Y, Takeda S. Crystal structure of the C-terminal domain of Mu phage central spike and functions of bound calcium ion. Biochim Biophys Acta. 2013 Jan;1834(1):284-91. doi: 10.1016/j.bbapap.2012.08.015., Epub 2012 Aug 24. PMID:22922659 doi:http://dx.doi.org/10.1016/j.bbapap.2012.08.015

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OCA

[1] Suzuki H, Yamada S, Toyama Y, Takeda S. The C-terminal domain is sufficient for host-binding activity of the Mu phage tail-spike protein. Biochim Biophys Acta. 2010 Sep;1804(9):1738-42. doi:, 10.1016/j.bbapap.2010.05.003. Epub 2010 May 15. PMID:20478417 doi:http://dx.doi.org/10.1016/j.bbapap.2010.05.003

[2] Harada K, Yamashita E, Nakagawa A, Miyafusa T, Tsumoto K, Ueno T, Toyama Y, Takeda S. Crystal structure of the C-terminal domain of Mu phage central spike and functions of bound calcium ion. Biochim Biophys Acta. 2013 Jan;1834(1):284-91. doi: 10.1016/j.bbapap.2012.08.015., Epub 2012 Aug 24. PMID:22922659 doi:http://dx.doi.org/10.1016/j.bbapap.2012.08.015

[1]

[2]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 3vtn is ON HOLD
+==The crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MAD==
+<StructureSection load='3vtn' size='340' side='right'caption='[[3vtn]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-Authors: Harada, K., Yamashita, E., Nakagawa, A., Takeda, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3vtn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Mu Escherichia virus Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VTN FirstGlance]. <br>
-Description: The crystal structure of the C-terminal domain of Mu phage central spike -Pt derivative for MAD
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtn OCA], [https://pdbe.org/3vtn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vtn RCSB], [https://www.ebi.ac.uk/pdbsum/3vtn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtn ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BP45_BPMU BP45_BPMU] Component of the baseplate that forms a central needlelike spike used to puncture the host cell membrane for tube insertion during virus entry. Probably involved in baseplate and tail assembly. Serves as the distal plug of tail tube channel and might regulate the process of the phage DNA and protein ejection into the host cell.<ref>PMID:20478417</ref> <ref>PMID:22922659</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia virus Mu]]
+[[Category: Large Structures]]
+[[Category: Harada K]]
+[[Category: Nakagawa A]]
+[[Category: Takeda S]]
+[[Category: Yamashita E]]

3vtn: Difference between revisions

Latest revision as of 11:41, 20 March 2024

The crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MADThe crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MAD

Structural highlights

Function

References

Contents

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3vtn: Difference between revisions

Latest revision as of 11:41, 20 March 2024

The crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MADThe crystal structure of the C-terminal domain of Mu phage central spike - Pt derivative for MAD

Structural highlights

Function

References

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