2hig: Difference between revisions

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==Crystal Structure of Phosphofructokinase apoenzyme from Trypanosoma brucei.==
The line below this paragraph, containing "STRUCTURE_2hig", creates the "Structure Box" on the page.
<StructureSection load='2hig' size='340' side='right'caption='[[2hig]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hig]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HIG FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_2hig|  PDB=2hig  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hig OCA], [https://pdbe.org/2hig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hig RCSB], [https://www.ebi.ac.uk/pdbsum/2hig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hig ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Phosphofructokinase apoenzyme from Trypanosoma brucei.===
== Function ==
 
[https://www.uniprot.org/uniprot/PFKA_TRYBB PFKA_TRYBB] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03186]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/2hig_consurf.spt"</scriptWhenChecked>
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[2hig]] is a 2 chain structure of [[Phosphofructokinase (PFK)]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIG OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hig ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphofructokinase (PFK)|Phosphofructokinase (PFK)]]
*[[Phosphofructokinase 3D structures|Phosphofructokinase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:017207816</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: 6-phosphofructokinase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Fothergill-Gilmore, L A.]]
[[Category: Fothergill-Gilmore LA]]
[[Category: Martinez-Oyanedel, J.]]
[[Category: Martinez-Oyanedel J]]
[[Category: McNae, I W.]]
[[Category: McNae IW]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw MD]]
[[Category: Transferase]]

Latest revision as of 12:32, 14 February 2024

Crystal Structure of Phosphofructokinase apoenzyme from Trypanosoma brucei.Crystal Structure of Phosphofructokinase apoenzyme from Trypanosoma brucei.

Structural highlights

2hig is a 2 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PFKA_TRYBB Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03186]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2hig, resolution 2.40Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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