4f4y: Difference between revisions

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-'''Unreleased structure'''
-The entry 4f4y is ON HOLD
+==Y-family DNA polymerase chimera Dbh-Dpo4-Dbh==
+<StructureSection load='4f4y' size='340' side='right'caption='[[4f4y]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4f4y]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2], [https://en.wikipedia.org/wiki/Sulfolobus_acidocaldarius_DSM_639 Sulfolobus acidocaldarius DSM 639] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F4Y FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.338&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DCP:2-DEOXYCYTIDINE-5-TRIPHOSPHATE'>DCP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f4y OCA], [https://pdbe.org/4f4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f4y RCSB], [https://www.ebi.ac.uk/pdbsum/4f4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f4y ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[https://www.uniprot.org/uniprot/DPO4_SULAC DPO4_SULAC] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis (By similarity).
-Authors: Pata, J.D., Wilson, R.C.
+==See Also==
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
-Description: The Inter-Domain Linker is a Major Determinant of Y-Family Polymerase Activity, Fidelity and Translesion Specificity
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Saccharolobus solfataricus P2]]
+[[Category: Sulfolobus acidocaldarius DSM 639]]
+[[Category: Synthetic construct]]
+[[Category: Pata JD]]
+[[Category: Wilson RC]]