4drq: Difference between revisions

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-[[Image:4drq.png|left|200px]]
-<!--
+==Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid==
-The line below this paragraph, containing "STRUCTURE_4drq", creates the "Structure Box" on the page.
+<StructureSection load='4drq' size='340' side='right'caption='[[4drq]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[4drq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRQ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0OS:{3-[(1S)-1-[({(2S)-1-[(3,5-DICHLOROPHENYL)SULFONYL]PIPERIDIN-2-YL}CARBONYL)OXY]-3-(3,4-DIMETHOXYPHENYL)PROPYL]PHENOXY}ACETIC+ACID'>0OS</scene></td></tr>
-{{STRUCTURE_4drq|  PDB=4drq  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drq OCA], [https://pdbe.org/4drq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drq RCSB], [https://www.ebi.ac.uk/pdbsum/4drq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drq ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
-===Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid===
+==See Also==
+*[[FKBP 3D structures|FKBP 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_22455398}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 22455398 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_22455398}}
-==About this Structure==
-[[4drq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRQ OCA].
-==Reference==
-<ref group="xtra">PMID:022455398</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Peptidylprolyl isomerase]]
+[[Category: Large Structures]]
-[[Category: Bracher, A.]]
+[[Category: Bracher A]]
-[[Category: Gopalakrishnan, R.]]
+[[Category: Gopalakrishnan R]]
-[[Category: Hausch, F.]]
+[[Category: Hausch F]]
-[[Category: Hoogeland, B.]]
+[[Category: Hoogeland B]]
-[[Category: Kozany, C.]]
+[[Category: Kozany C]]
-[[Category: Schneider, S.]]
+[[Category: Schneider S]]
-[[Category: Wang, Y.]]
+[[Category: Wang Y]]
-[[Category: Fk-506 binding domain]]
-[[Category: Hsp90 cochaperone]]
-[[Category: Immunophilin]]
-[[Category: Isomerase]]
-[[Category: Peptidyl-prolyl isomerase]]